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Search Results for " anti-inflammatory active "

20

Compounds

Cat No. Product Name Synonyms Targets
T1560 Prednisolone Predonine,Hydroretrocortine,Metacortandralone Glucocorticoid Receptor , Endogenous Metabolite
Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
T30937 Cimicoxib UR-8880,UR8880,trade name: Cimalgex COX
Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.
T2648 Pimecrolimus SDZ-ASM 981,ASM 981 Others
Pimecrolimus (SDZ-ASM 981), a calcineurin inhibitor immunosuppressant, binds to the receptor macrophilin-12 (FKBP-12) forming a complex that blocks the calcium-dependent signal transduction cascade mediated by calcineuri...
T27061 CP-24879 hydrochloride CP-24879 HCl Others
CP-24879 hydrochloride (CP-24879 HCl), a Δ5D/Δ6D dual-inhibitor, can significantly reduce intracellular lipid accumulation and inflammatory injury in hepatocytes. CP-24879 hydrochloride exhibits superior antisteatotic an...
T2755 Rhoifolin Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
TN6774 Emodin 6-O-β-D-glucoside Glucoemodin Others
Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside ...
T3417 Amentoflavone Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal
Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib...
T14546 Bermoprofen AD-1590,AJ-1590 Others
Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.
T28698 SC-22716 SC 22716,SC22716 Aminopeptidase
SC-22716 is an orally active leukotriene A4 (LTA4) hydrolase inhibitor.SC-22716 has potential anti-inflammatory activity and may be used in the study of inflammatory bowel disease and psoriasis.
T64359 Anti-inflammatory agent 36 Immunology/Inflammation related
Anti-inflammatory agent 36 is an anti-inflammatory agent. It exhibited dose-dependent inhibition of LPS-induced release of TNF-a and IL-6 in active RAW 264.7 mouse macrophages, IC50=3.69uM and 3.68uM, respectively.
T12862 SC58451 COX
SC58451 is a novel potent, orally active and selective COX-2 inhibitor.SC58451 showed anti-inflammatory activity in a rat model of arthritis.
T40377 Nicotredole Tryptamide Others
Nicotredole (Tryptamide) (Tryptamide) is an orally active analgesic and anti-inflammatory agent. Nicotredole exhibits evident anti-inflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak...
T0244 Tilorone dihydrochloride Influenza Virus , HIF/HIF Prolyl-Hydroxylase , IFNAR
Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.
T4955 Saponaretin Isovitexin,Apigenin-6-C-glucoside Apoptosis , Antioxidant
saponaretin, an active component of many traditional Chinese medicines, shows various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on.
T10152 4-Methylamino antipyrine COX , Drug Metabolite
4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methylamino antipyrine has analgesic, antipyretic, and relativel...
T27312 Fentiazac Donorest,Flogene,BR-700 Others
Fentiazac(BR-700) is an orally active nonsteroidal alkanoic acid derivative with significant analgesic, anti-inflammatory, and antipyretic activity.Fentiazac is used in the study of inflammatory diseases such as rheumato...
T31083 CP-868388 free base CP868388,CP 868388,(-)-CP-868388,UNII-999KY5ZIGB,CP-868388 PPAR
CP-868388 free base (CP-868388) is an orally active, potent and selective PPARα agonist with hypolipidemic and anti-inflammatory activity for the study of dyslipidemia.
T36716 RO0270608 Integrin
RO0270608, the active metabolite of R411, is an orally active dual α4β1/α4β7 integrin antagonist with anti-inflammatory activity that modulates inflammation and can be used in the study of allergic inflammatory responses...
T6S0630 Hypaconitine P450 , TNF
Hypaconitine, an active and highly toxic constituent derived from Aconitum species, has anti-inflammatory activity, is widely used to treat rheumatism.
T12883 Fezagepras PBI-4050,Setogepram GPR
Fezagepras (Setogepram) is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84 with anti-inflammatory, anti-fibrotic, and anti-proliferative actions.

Compounds

Prednisolone
T1560
Synonym: Predonine,Hydroretrocortine,Metacortandralone
Target: Glucocorticoid Receptor, Endogenous Metabolite
Cimicoxib
T30937
Synonym: UR-8880,UR8880,trade name: Cimalgex
Target: COX
Pimecrolimus
T2648
Synonym: SDZ-ASM 981,ASM 981
Target: Others
CP-24879 hydrochloride
T27061
Synonym: CP-24879 HCl
Target: Others
Rhoifolin
T2755
Synonym: Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
Emodin 6-O-β-D-glucoside
TN6774
Synonym: Glucoemodin
Target: Others
Amentoflavone
T3417
Synonym: Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin
Target: Apoptosis, P450, Phospholipase, Reactive Oxygen Species, Opioid Receptor, COX, Antibacterial, RSV, Antifungal
Bermoprofen
T14546
Synonym: AD-1590,AJ-1590
Target: Others
SC-22716
T28698
Synonym: SC 22716,SC22716
Target: Aminopeptidase
Anti-inflammatory agent 36
T64359
Synonym:
Target: Immunology/Inflammation related
SC58451
T12862
Synonym:
Target: COX
Nicotredole
T40377
Synonym: Tryptamide
Target: Others
Tilorone dihydrochloride
T0244
Synonym:
Target: Influenza Virus, HIF/HIF Prolyl-Hydroxylase, IFNAR
saponaretin
T4955
Synonym: Isovitexin,Apigenin-6-C-glucoside
Target: Apoptosis, Antioxidant
4-Methylamino antipyrine
T10152
Synonym:
Target: COX, Drug Metabolite
Fentiazac
T27312
Synonym: Donorest,Flogene,BR-700
Target: Others
CP-868388 free base
T31083
Synonym: CP868388,CP 868388,(-)-CP-868388,UNII-999KY5ZIGB,CP-868388
Target: PPAR
RO0270608
T36716
Synonym:
Target: Integrin
Hypaconitine
T6S0630
Synonym:
Target: P450, TNF
Fezagepras
T12883
Synonym: PBI-4050,Setogepram
Target: GPR
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TargetMol